UnivTrevesV1, Main, Exploration, bibRecord, 001592

Angiographic results of the first human experience with the biolimus A9 drug-eluting stent for de novo coronary lesions

Identifieur interne : 001592 ( Main/Exploration ); précédent : 001591; suivant : 001593

Angiographic results of the first human experience with the biolimus A9 drug-eluting stent for de novo coronary lesions

Auteurs : Ricardo A. Costa [États-Unis] ; Alexandra J. Lansky [États-Unis] ; Alexandre Abizaid [Brésil] ; Ralph Müeller [Allemagne] ; Yoshihiro Tsuchiya [États-Unis] ; Ken Mori [États-Unis] ; Ecaterina Cristea [États-Unis] ; Martin B. Leon [États-Unis] ; J. Eduardo Sousa [Brésil] ; Thomas Schmidt [Allemagne] ; Karl E. Hauptmann [Allemagne] ; Eberhard Grube [Allemagne]

Source :

The American journal of cardiology [ 0002-9149 ] ; 2006.

RBID : Pascal:06-0407493

Descripteurs français

Pascal (Inist)
- Cardiopathie coronaire, Angiographie, Résultat, Homme, De novo, Artère coronaire, Lésion, Appareil circulatoire, Cardiologie, Phlébologie, Stent à élution médicamenteuse.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Angiography, Cardiology, Circulatory system, Coronary artery, Coronary heart disease, De novo, Drug eluting stent, Human, Lesion, Phlebology, Result.

Abstract

This report describes angiographic findings of the first-in-human evaluation of the Biolimus A9 drug-eluting stent (Biolimus stent) in the treatment of noncomplex coronary lesions. In total, 120 patients with 122 de novo coronary lesions (2.75- to 4.00-mm vessels, ≤24-mm lesion length) were prospectively randomized in a 2:1 ratio to receive the Biolimus stent (n = 80, 82 lesions) or the control uncoated stent (n = 40). Baseline lesion and angiographic characteristics were similar between groups. At 6-month follow-up, late lumen loss was significantly decreased with the Biolimus stent in the stent (0.26 ± 0.43 vs 0.74 ± 0.45 mm, p <0.001) and in the segment (0.14 ± 0.45 vs 0.40 ± 0.41 mm, p = 0.004). In-stent restenosis was 3.9% in the Biolimus stent group versus 7.7% in the control group (p = 0.40). There was no exaggerated hyperplasia at the proximal and/or distal edge of the stent.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000971
to stream PascalFrancis, to step Curation: 000507
to stream PascalFrancis, to step Checkpoint: 000780
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to stream Main, to step Curation: 001592

Le document en format XML

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<series><title level="j" type="main">The American journal of cardiology</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Angiography</term>
<term>Cardiology</term>
<term>Circulatory system</term>
<term>Coronary artery</term>
<term>Coronary heart disease</term>
<term>De novo</term>
<term>Drug eluting stent</term>
<term>Human</term>
<term>Lesion</term>
<term>Phlebology</term>
<term>Result</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Cardiopathie coronaire</term>
<term>Angiographie</term>
<term>Résultat</term>
<term>Homme</term>
<term>De novo</term>
<term>Artère coronaire</term>
<term>Lésion</term>
<term>Appareil circulatoire</term>
<term>Cardiologie</term>
<term>Phlébologie</term>
<term>Stent à élution médicamenteuse</term>
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<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
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<front><div type="abstract" xml:lang="en">This report describes angiographic findings of the first-in-human evaluation of the Biolimus A9 drug-eluting stent (Biolimus stent) in the treatment of noncomplex coronary lesions. In total, 120 patients with 122 de novo coronary lesions (2.75- to 4.00-mm vessels, ≤24-mm lesion length) were prospectively randomized in a 2:1 ratio to receive the Biolimus stent (n = 80, 82 lesions) or the control uncoated stent (n = 40). Baseline lesion and angiographic characteristics were similar between groups. At 6-month follow-up, late lumen loss was significantly decreased with the Biolimus stent in the stent (0.26 ± 0.43 vs 0.74 ± 0.45 mm, p <0.001) and in the segment (0.14 ± 0.45 vs 0.40 ± 0.41 mm, p = 0.004). In-stent restenosis was 3.9% in the Biolimus stent group versus 7.7% in the control group (p = 0.40). There was no exaggerated hyperplasia at the proximal and/or distal edge of the stent.</div>
</front>
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Angiographic results of the first human experience with the biolimus A9 drug-eluting stent for de novo coronary lesions

Angiographic results of the first human experience with the biolimus A9 drug-eluting stent for de novo coronary lesions

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